Our publications
2022
Pharmacokinetics of ribavirin in the treatment of Lassa fever: An observational clinical study at the Irrua Specialist Teaching Hospital, Edo State, Nigeria
- Groger M, Akhideno P, Kleist CJ, Babatunde FO, Edeawe O, Hinzmann J, Akhigbe T, Nwatuzor J, Eifediyi G, Müller J, Hinrichs M, Pahlmann M, Sarpong FN, Wagner C, Thielebein A, Aihonwalan L, Koch T, Riedner M, Ogbaini-Emovon E, Okogbenin S, Günther S, Wicha SG, Ramharter M, Oestereich L, Duraffour S, Erameh C
- Clin Infect Dis. 2023 Feb 8;76(3):e841-e848. doi: 10.1093/cid/ciac578
Effectiveness of pyronaridine-artesunate against Plasmodium malariae, Plasmodium ovale spp, and mixed-Plasmodium infections: a post-hoc analysis of the CANTAM-Pyramax trial
- Groger M, Tona Lutete G, Mombo-Ngoma G, Ntamabyaliro NY, Kahunu Mesia G, Muena Mujobu TB, Dimessa Mbadinga LB, Zoleko Manego R, Egger-Adam D, Borghini-Fuhrer I, Shin J, Miller R, Arbe-Barnes S, Duparc S, Ramharter M
- Lancet Microbe. 2022 Aug;3(8):e598-e605. doi: 10.1016/S2666-5247(22)00092-1
Challenges in the clinical development pathway for triple and multiple drug combinations in the treatment of uncomplicated falciparum malaria
- Bassat Q, Maïga-Ascofaré O, May J, Clain J, Mombo-Ngoma G, Groger M, Adegnika AA, Agobé JD, Djimde A, Mischlinger J, Ramharter M on behalf of ASAAP and Multimal Consortia
- Malar J. 2022 Feb 22;21(1):61. doi: 10.1186/s12936-022-04079-9
2021
Diagnostic performance of capillary and venous blood samples in the detection of Loa loa and Mansonella perstans microfilaraemia using light microscopy
- Mischlinger J, Manego RZ, Mombo-Ngoma G, Ekoka Mbassi D, Hackbarth N, Ekoka Mbassi FA, Davi SD, Kreuzmair R, Veletzky L, Hergeth J, Ndoumba WN, Pitzinger P, Groger M, Matsiegui PB, Adegnika AA, Agnandji ST, Lell B, Ramharter M
- PLoS Negl Trop Dis. 2021 Aug 16;15(8):e0009623. doi: 10.1371/journal.pntd.0009623
Pyronaridine-artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study
- Tona Lutete G, Mombo-Ngoma G, Assi SB, Bigoga JD, Koukouikila-Koussounda F, Ntamabyaliro NY, Ntoumi F, Agnandji ST, Groger M, Shin J, Borghini-Fuhrer I, Arbe-Barnes S, Allen SJ, Kremsner PG, Miller R, Duparc S, Ramharter M, the CANTAM study group
- PLoS Med. 2021 Jun 15;18(6):e1003669. doi: 10.1371/journal.pmed.1003669
2020
Prospective observational study on the pharmacokinetic properties of the Irrua ribavirin regimen used in routine clinical practice in patients with Lassa fever in Nigeria
- Erameh C, Edeawe O, Akhideno P, Eifediyi G, Omansen TF, Wagner C, Sarpong F, Koch T, Wicha S, Kurth F, Duraffour S, Oestereich L, Pahlmann M, Okogbenin S, Ogbaini-Emovon E, Günther S, Ramharter M, Groger M
- BMJ Open. 2020 Apr 16;10(4):e036936. doi: 10.1136/bmjopen-2020-036936
2019
Reply to Lin et al.
- Groger M, Ramharter M
- Clinical Infectious Diseases. 70(9):2019–2020
Ribavirin for the treatment of Lassa fever: A systematic review and meta-analysis
- Eberhardt KA, Mischlinger J, Jordan S, Groger M, Günther S, Ramharter M
- International Journal of Infectious Diseases. 2019 Oct;87:15-20. doi: 10.1016/j.ijid.2019.07.01
Prospective clinical and molecular evaluation of potential plasmodium ovale curtisi and wallikeri relapses in a high-transmission setting
- Groger M, Veletzky L, Lalremruata A, Cattaneo C, Mischlinger J, Manego Zoleko R, Kim J, Klicpera A, Meyer EL, Blessborn D, Winterberg M, Adegnika AA, Agnandji ST, Kremsner PG, Mordmüller B, Mombo-Ngoma G, Fuehrer HP, Ramharter M
- Clinical Infectious Diseases. 2019 Nov 27;69(12):2119-2126. doi: 10.1093/cid/ciz131
FDG-PET/MRI imaging for the management of alveolar echinococcosis: initial clinical experience at a reference centre in Austria
- Lötsch F, Waneck F, Groger M, Auer H, Kaczirek K, Rausch I, Wadsak W, Hacker M, Lagler H, Ramharter M, Karanikas G
- Tropical Medicine & International Health. 2019 Jun;24(6):663-670. doi: 10.1111/tmi.13228
2018
Validity and reliability of methods to microscopically detect and quantify malaria parasitaemia
- Mischlinger J, Pitzinger P, Veletzky L, Groger M, Zoleko-Manego R, Adegnika AA, Agnandji ST, Lell B, Kremsner PG, Mombo-Ngoma G, Mordmüller B, Ramharter M
- Tropical Medicine & International Health. 2018 Sep;23(9):980-991. doi: 10.1111/tmi.13124
Preliminary Evidence for the Absence of Cystic Echinococcosis in Gabon: A Cross-Sectional Pilot Survey in Humans and Definitive Hosts
- Lötsch F, Mombo-Ngoma G, Mischlinger J, Groger M, Veletzky L, Adegnika AA, Lell B, Agnandji ST, Bouyou-Akotet M, Obermüller M, Wassermann M, Schneider R, Auer H, Ramharter M
- Am J Trop Med Hyg. 2018 Jul;99(1):97-101. doi: 10.4269/ajtmh.17-0955
Use of Capillary Blood Samples Leads to Higher Parasitemia Estimates and Higher Diagnostic Sensitivity of Microscopic and Molecular Diagnostics of Malaria than Venous Blood Samples
- Mischlinger J, Pitzinger P, Veletzky L, Groger M, Zoleko-Manego R, Adegnika AA, Agnandji ST, Lell B, Kremsner PG, Tannich E, Mombo-Ngoma G, Mordmüller B, Ramharter M
- The Journal of Infectious Diseases. 2018 Sep 8;218(8):1296-1305. doi: 10.1093/infdis/jiy319
Detection of the Malaria causing Plasmodium Parasite in Saliva from Infected Patients using Topoisomerase I Activity as a Biomarker
- Hede MS, Fjelstrup S, Lötsch F, Zoleko RM, Klicpera A, Groger M, Mischlinger J, Endame L, Veletzky L, Neher R, Simonsen AKW, Petersen E, Mombo-Ngoma G, Stougaard M, Ho YP, Labouriau R, Ramharter M, Knudsen BR
- Sci Rep. 2018 Mar 7;8(1):4122. doi: 10.1038/s41598-018-22378-7
Prospective Clinical Trial Assessing Species-Specific Efficacy of Artemether-Lumefantrine for the Treatment of Plasmodium malariae, Plasmodium ovale, and Mixed Plasmodium Malaria in Gabon
- Groger M, Veletzky L, Lalremruata A, Cattaneo C, Mischlinger J, Zoleko-Manego R, Endamne L, Klicpera A, Kim J, Nguyen T, Flohr L, Remppis J, Matsiegui PB, Adegnika AA, Agnandji ST, Kremsner PG, Mordmüller B, Mombo-Ngoma G, Ramharter M
- Antimicrobial Agents and Chemotherapy. 2018 Feb 23;62(3):e01758-17. doi: 10.1128/AAC.01758-17
Molecular evidence for relapse of an imported Plasmodium ovale wallikeri infection
- Veletzky L, Groger M, Lagler H, Walochnik J, Auer H, Fuehrer HP, Ramharter M
- Malaria Journal. 2018 Feb 9;17(1):78. doi: 10.1186/s12936-018-2226-4
2017
Efficacy and safety of fosmidomycin-piperaquine as non-artemisinin-based combination therapy for uncomplicated falciparum malaria - A single-arm, age-de-escalation proof of concept study in Gabon
- Mombo-Ngoma G, Remppis J, Sievers M, Zoleko Manego R, Endamne L, Kabwende L, Veletzky L, Nguyen TT, Groger M, Lötsch F, Mischlinger J, Flohr L, Kim J, Cattaneo C, Hutchinson D, Duparc S, Moehrle J, Velavan TP, Lell B, Ramharter M, Adegnika AA, Mordmüller B, Kremsner PG
- Clin Infect Dis. 2018 Jun 1;66(12):1823-1830. doi: 10.1093/cid/cix1122
A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria
- Macintyre F, Adoke Y, Tiono AB, Duong TT, Mombo-Ngoma G, Bouyou-Akotet M, Tinto H, Bassat Q, Issifou S, Adamy M, Demarest H, Duparc S, Leroy D, Laurijssens BE, Biguenet S, Kibuuka A, Tshefu AK, Smith M, Foster C, Leipoldt I, Kremsner PG, Phuc BQ, Ouedraogo A, Ramharter M on behalf of the OZ-Piperaquine Study Group
- BMC Med. 2017 Oct 9;15(1):181. doi: 10.1186/s12916-017-0940-3
A systematic review of the clinical presentation, treatment and relapse characteristics of human Plasmodium ovale malaria
- Groger M, Fischer HS, Veletzky L, Lalremruata A, Ramharter M
- Malar J. 2017 Mar 11;16(1):112. doi: 10.1186/s12936-017-1759-2
2016
Seroprevalence of Toxocara spp. in a rural population in Central African Gabon
- Lötsch F, Obermüller M, Mischlinger J, Mombo-Ngoma G, Groger M, Adegnika AA, Agnandji ST, Schneider R, Auer H, Ramharter M
- Parasitology International. 2016 Dec;65(6 Pt A):632-634. doi: 10.1016/j.parint.2016.09.001
Intra-cystic concentrations of albendazole-sulphoxide in human cystic echinococcosis: a systematic review and analysis of individual patient data
- Lötsch F, Naderer J, Skuhala T, Groger M, Auer H, Kaczirek K, Waneck F, Ramharter M
- Parasitology Research. 2016 Aug;115(8):2995-3001. doi: 10.1007/s00436-016-5054-x
Effect of mild medical hypothermia on in vitro growth of Plasmodium falciparum and the activity of anti-malarial drugs
- Rehman K, Sauerzopf U, Veletzky L, Lötsch F, Groger M, Ramharter M
- Malar J. 2016 Mar 15;15:162. doi: 10.1186/s12936-016-1215-8
2015
Streptococcus agalactiae Serotype Distribution and Antimicrobial Susceptibility in Pregnant Women in Gabon, Central Africa
- Belard S, Toepfner N, Capan-Melser M, Mombo-Ngoma G, Zoleko-Manego R, Groger M, Matsiegui PB, Agnandji ST, Adegnika AA, González R, Kremsner PG, Menendez C, Ramharter M, Berner R
- Scientific Reports. 2015 Nov 25;5:17281. doi: 10.1038/srep1728
Epidemiology of Human Herpes Virus 8 in Pregnant Women and their Newborns--A cross-sectional delivery survey in Central Gabon
- Capan-Melser M, Mombo-Ngoma G, Akerey-Diop D, Basra A, Manego-Zoleko R, Würbel H, Lötsch F, Groger M, Skoll M, Schwing J, Schipulle U, Matsiegui PB, González R, Menendez C, Kremsner PG, Adegnika AA, Agnandji ST, Ramharter M
- Int J Infect Dis. 2015 Oct;39:16-9. doi: 10.1016/j.ijid.2015.08.004
Adherence of patients to long-term medication: a cross-sectional study of antihypertensive regimens in Austria
- Lötsch F, Auer-Hackenberg L, Groger M, Rehman K, Morrison V, Holmes E, Parveen S, Plumpton C, Clyne W, de Geest S, Dobbels F, Vrijens B, Kardas P, Hughes D, Ramharter M
- Wien Klin Wochenschr. 2015 May;127(9-10):379-84. doi: 10.1007/s00508-015-0782-y
Evaluation of intermittent preventive treatment of malaria against group B Streptococcus colonization in pregnant women: a nested analysis of a randomized controlled clinical trial of sulfadoxine/pyrimethamine versus mefloquine
- Capan-Melser M, Mombo Ngoma G, Akerey-Diop D, Basra A, Würbel H, Groger M, Mackanga JR, Zoleko-Manego R, Schipulle U, Schwing J, Lötsch F, Rehman K, Matsiegui PB, Agnandji ST, Adegnika AA, Bélard S, González R, Kremsner PG, Menendez C, Ramharter M
- J Antimicrob Chemother. 2015;70(6):1898-902. doi: 10.1093/jac/dkv041
